andrewbonney.cloud // St. Louis, MO

Andrew Bonney

Bioinformatics Scientist | Multi-Omics & AI Integration

Washington University School of Medicine

Integrating multi-omic data and developing reproducible computational pipelines. From Nextflow and Docker to deep learning for epigenetic analysis — bridging industrial rigor with academic innovation.

01

Projects

7 entries

Active Deployments

Live
Bioinformatics

STL BCB Collective

A community platform for the St. Louis Bioinformatics & Computational Biology collective. Connecting researchers, developers, and scientists in the greater St. Louis area.

Bioinformatics Community Web
Live
Monitoring

Gateway Watch

A monitoring and analytics platform tracking real-time data streams. Built for reliability and performance in data-dense environments.

Monitoring Analytics TypeScript
Live
Security

DefLab

A defense and research laboratory platform for exploring computational methods in security analysis and threat modeling.

Security Research Python
Initializing...
Bioinformatics

EpiBench Lite

An interactive bioinformatics demo for epigenetic analysis. Upload genomic data, run methylation predictions, and visualize results in real-time.

Bioinformatics Python Machine Learning FastAPI

Research & Select Projects

Research
Nextflow

nf-core/scge Pipeline

Cloud-native tumor-normal sequencing pipeline for the NIH Common Fund's Somatic Cell Genome Editing program. Built with Nextflow DSL2 and DRAGEN hardware acceleration on AWS.

Nextflow AWS Batch DRAGEN nf-core Genomics
Research
Python

DeepLabCut Imaging Pipeline

Machine learning-based pose estimation system for tracking zebrafish behavior in custom experimental rigs, enabling high-throughput behavioral analysis.

Python DeepLabCut Computer Vision Pose Estimation
Research
BERT

BERT for Sequence Classification

Transformer-based language models applied to biological sequence classification, exploring gene function prediction and regulatory element annotation.

BERT Transformers NLP PyTorch Genomics
02

Technical Skills

28 capabilities
Languages lang://
Python advanced
R advanced
Bash proficient
Rust familiar
SQL proficient
Java familiar
Workflow & Cloud infra://
Nextflow DSL2 advanced
Docker/Singularity advanced
AWS (Batch, S3, EC2) proficient
Git/GitHub advanced
Linux/HPC Admin proficient
Bioinformatics bio://
GATK proficient
STAR / Bowtie2 proficient
SAMtools / BEDtools advanced
Seurat / DESeq2 proficient
Bismark / MACS proficient
Peakachu / HOMER proficient
BioPython / BioPerl proficient
Data Science & AI ai://
PyTorch advanced
TensorFlow proficient
Scikit-Learn advanced
Pandas / NumPy advanced
Explainable AI (SHAP, Captum) proficient
Computer Vision (CNNs) proficient
Regulatory & QC reg://
ISO 9001
FDA Validation (21 CFR Part 11)
GLP/GMP
Data Integrity & Audit Trails
advanced proficient familiar
03

Experience

7 entries
Aug 2024 — Present work St. Louis, MO

Bioinformatics Research Assistant

Washington University School of Medicine — Spencer Lab

Engineering reproducible Nextflow pipelines for multi-omic datasets (RNA-seq, WGBS, Hi-C) in AML research. Developing CNN/PyTorch frameworks for DNA methylation prediction. Orchestrating petabyte-scale ETL on AWS Batch/S3.

Nextflow PyTorch AWS Hi-C WGBS
May 2024 — Aug 2024 work Chesterfield, MO

Analytical R&D Data Scientist

Pfizer

Developed computer vision algorithms for high-content microscopy data. Replaced manual cell counting with reproducible R/Python scripts, increasing throughput by 300%. Reduced analysis error rates by 40%.

Computer Vision Python R Microscopy
Dec 2022 — Dec 2024 education St. Louis, MO

M.S. Bioinformatics & Computational Biology

Saint Louis University

GPA: 3.97/4.00. Graduate research in deep learning for structural RNA classification, molecular dynamics simulations of drug-receptor interactions, and benchmarking methylation detection pipelines.

Neural Networks Molecular Dynamics Benchmarking
Jul 2021 — Jan 2024 work St. Louis, MO

Scientist II — Biochemistry & Instrumental Analysis

ThermoFisher Scientific

Technical Lead for analytical biochemistry assays. Built Python parsers for automated instrument data ingestion (CGE, PCR). Maintained 99.8% data accuracy across 200+ monthly samples.

Python Analytical Chemistry Automation
May 2021 — Aug 2021 work St. Louis, MO

QC Scientist — Analytical Chemistry

Firmenich

Processed and verified high-volume GC-MS spectral data for 150+ compounds under strict data integrity standards.

GC-MS Quality Control
Aug 2020 — May 2021 work Creve Coeur, MO

Genetic QA Lab Technician

Bayer

High-throughput DNA extractions using Biomek automation systems, processing 500+ samples weekly in an ISO 9001 compliant quality lab.

DNA Extraction Automation ISO 9001
Aug 2015 — May 2019 education Kansas City, MO

B.S. Biology

University of Missouri–Kansas City

Undergraduate studies in biological sciences with emphasis on molecular biology and genetics.

Biology Genetics
04

The Lab

[experimental]
epibench-lite
v0.1.0-alpha
$ epibench init --mode=lite

info Loading methylation prediction model...

warn Backend API not yet connected

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EpiBench Lite is a browser-based demo for epigenetic analysis.

Upload CSV or FASTA files, run methylation predictions via

the FastAPI backend, and visualize results in real-time.

$ _
Python · pandas · scikit-learn · FastAPI Open Lab ↗